Overview

SCIENTIFIC SCORE
Questionable
Based on 2 Researches
5
USERS' SCORE
Good
Based on 2 Reviews
8.5
Supplement Facts
Serving Size: 1 Softgel
Amount Per Serving
%DV
Vitamin A(60% as Beta-Carotene and 40% from Fish Liver Oil)
7,500 mcg
833%
Vitamin D3(as Cholecalciferol) (from Lanolin)
25 mcg (1,000 IU)
125%

Top Medical Research Studies

We conducted a thorough investigation into whether high-dose intermittent vitamin D3 could alleviate symptoms of chronic fatigue syndrome (CFS) and improve vascular health. This double-blind, randomized placebo-controlled trial involved patients meeting established criteria for CFS. Participants received either 100,000 units of vitamin D3 or a placebo every two months for six months.

Over the course of the study, we measured key outcomes such as arterial stiffness, blood pressure, cholesterol levels, and fatigue levels through various tests. Surprisingly, our findings showed that vitamin D3 treatment did not lead to any significant improvements in these areas. We observed only a slight increase in vitamin D levels in the treatment group, but this did not translate into better vascular health or reduced fatigue.

In conclusion, we honestly found that high-dose vitamin D3 did not offer any notable benefits for patients struggling with chronic fatigue syndrome. This study highlights the complexities of treating CFS and suggests that vitamin D3 may not be the solution some had hoped for.
8
Beta-glucan shows cognitive improvements
We conducted a randomized, double-blind, placebo-controlled trial to explore how yeast beta-glucan, along with multivitamins, affects individuals suffering from Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS). In our study, 65 participants received either beta-glucan combined with vitamins and zinc or a placebo for 36 weeks.

Interestingly, while our primary focus was on beta-glucan, which was shown to significantly improve cognitive fatigue, the role of vitamin D3 within this combination was not clearly established. This makes it challenging to directly assess the impact of vitamin D3 alone on chronic fatigue syndrome outcomes.

Overall, we discovered that beta-glucan supplementation could positively influence cognitive fatigue, offering promise for future research on nutritional support in ME/CFS patients. However, definitive conclusions about vitamin D3's effectiveness remain inconclusive due to the combined nature of the treatment.

Most Useful Reviews

9
Improved eye condition
1 people found this helpful
I took vitamin A for prevention, and the dosage is excellent. I give it to everyone in the family, as vit A is essential. We took 2-3 capsules during the initial peak of illness, then 1 capsule thereafter. With other vitamins, we swiftly overcame the disease. I also noticed my dry eyes disappeared, which I often had while wearing lenses. With vit A, E, and D, these issues are resolved. I recommend taking vit A in courses, twice a year for a month as advised by my doctor.
7.5
Less fatigue noticed
A fantastic option with perfect dosage! I regularly take vitamin A and increase my vitamin D to 2000 during winter. The quality and size of the capsules are excellent. I've noticed significant improvements: my hair and skin are healthier, fatigue has decreased, and my mood is more stable. I take them in the morning after breakfast for better absorption.

Medical Researches

SCIENTIFIC SCORE
Questionable
Based on 2 Researches
5
  • All Researches
8
Beta-glucan shows cognitive improvements
We conducted a randomized, double-blind, placebo-controlled trial to explore how yeast beta-glucan, along with multivitamins, affects individuals suffering from Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS). In our study, 65 participants received either beta-glucan combined with vitamins and zinc or a placebo for 36 weeks.

Interestingly, while our primary focus was on beta-glucan, which was shown to significantly improve cognitive fatigue, the role of vitamin D3 within this combination was not clearly established. This makes it challenging to directly assess the impact of vitamin D3 alone on chronic fatigue syndrome outcomes.

Overall, we discovered that beta-glucan supplementation could positively influence cognitive fatigue, offering promise for future research on nutritional support in ME/CFS patients. However, definitive conclusions about vitamin D3's effectiveness remain inconclusive due to the combined nature of the treatment.
We conducted a thorough investigation into whether high-dose intermittent vitamin D3 could alleviate symptoms of chronic fatigue syndrome (CFS) and improve vascular health. This double-blind, randomized placebo-controlled trial involved patients meeting established criteria for CFS. Participants received either 100,000 units of vitamin D3 or a placebo every two months for six months.

Over the course of the study, we measured key outcomes such as arterial stiffness, blood pressure, cholesterol levels, and fatigue levels through various tests. Surprisingly, our findings showed that vitamin D3 treatment did not lead to any significant improvements in these areas. We observed only a slight increase in vitamin D levels in the treatment group, but this did not translate into better vascular health or reduced fatigue.

In conclusion, we honestly found that high-dose vitamin D3 did not offer any notable benefits for patients struggling with chronic fatigue syndrome. This study highlights the complexities of treating CFS and suggests that vitamin D3 may not be the solution some had hoped for.

User Reviews

USERS' SCORE
Good
Based on 2 Reviews
8.5
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9
Improved eye condition
1 people found this helpful
I took vitamin A for prevention, and the dosage is excellent. I give it to everyone in the family, as vit A is essential. We took 2-3 capsules during the initial peak of illness, then 1 capsule thereafter. With other vitamins, we swiftly overcame the disease. I also noticed my dry eyes disappeared, which I often had while wearing lenses. With vit A, E, and D, these issues are resolved. I recommend taking vit A in courses, twice a year for a month as advised by my doctor.
7.5
Less fatigue noticed
A fantastic option with perfect dosage! I regularly take vitamin A and increase my vitamin D to 2000 during winter. The quality and size of the capsules are excellent. I've noticed significant improvements: my hair and skin are healthier, fatigue has decreased, and my mood is more stable. I take them in the morning after breakfast for better absorption.

Frequently Asked Questions

No FAQs are available for this product and symptom.

References

  1. Lacasa M, Alegre-Martin J, Sentañes RS, Varela-Sende L, Jurek J, et al. Yeast Beta-Glucan Supplementation with Multivitamins Attenuates Cognitive Impairments in Individuals with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: A Randomized, Double-Blind, Placebo-Controlled Trial. Nutrients. 2023;15. doi:10.3390/nu15214504
  2. Witham MD, Adams F, McSwiggan S, Kennedy G, Kabir G, et al. Effect of intermittent vitamin D3 on vascular function and symptoms in chronic fatigue syndrome--a randomised controlled trial. Nutr Metab Cardiovasc Dis. 2015;25:287. doi:10.1016/j.numecd.2014.10.007
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